Exact(1)
This structure should enable the rational design of new boronic acid derivatives with improved affinities and specificities for individual active subunits.
Similar(58)
Chemokines act as leukocyte chemoattractants with fine specificity for individual leukocyte types.
Mature tRNA degradation occurs with little specificity for individual tRNA species and on the hour time-scale, indicating that degradation of mature tRNA plays only a minor role in the regulation of tRNA distribution.
Non-classical NLSs that bind directly to importin β family members are less well defined and show specificity for individual importins.
However, the cleavage specificity for individual substrates, as illustrated in Figure 4 for ApoA-IV, can vary significantly, which suggests differences in the substrate proteolytic activity between the BCP and the HP examined.
Since the Arp2/3 complex is involved in diverse actin cytoskeletal functions, specificity for individual processes and morphological features can only be brought about by distinct regulatory pathways and by further accessory components of this core actin nucleation machinery.
Furthermore, agnathan fish possess an adaptive immune system based entirely on clonal rearrangement of LRRs rather than immunoglobulins and the resulting LRR domains demonstrate specificity for individual strains of bacteria [33] [36].
Compounds may be altered in body compartments so that their specificity for individual MMPs is altered.
The sensitivity and specificity for individual GPs were also generated and summarised.
Of these 13 QTL regions, five displayed specificity for individual compounds (Table 4).
Further specificity for individual monosaccharides results from local contacts with residues near the Ca2+ site.
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