It poses exquisite sequence-specificity and unique structures at different metabolic states, and is also a widely targeted molecule by many anticancer drugs [37], [38].
Detailed structural analyses have revealed specific and unique features of different SH2 domains suggesting that these domains, while ubiquitous and highly conserved, nevertheless exhibit unique specificity determining features.
Anti-oligo/polysialic acid antibodies often have DP-dependent antigenic specificity, and such unique antibodies are often used in biological studies for the detection and differentiation of oligo/polysialic acids.
However, in vivo Hox proteins possess a high degree of target specificity and regulate unique suites of genes within their respective domains.
Therefore, the enrichment of retrotransposons in O. polyrhachis-furcata and O. sinensis could be related to their high host specificity and a unique pathogenicity compared to the other insect fungi.
Yet the specificity, the sensitive and unique nature of being female, could be considered as disparate from the male experience as being black is to a white person, but that hasn't stopped male authors, from Vladimir Nabokov to Wally Lamb, from creating their women of note.
The selectivity and specificity, the unique pharmacokinetics, and the ability to engage and activate the host immune system differentiate these biologics from traditional small molecule anticancer drugs.
Multivalent recombinant antibody fragments provide high binding avidity and unique specificity to a wide range of target antigens and haptens.
Analysis of natural host-parasite relationships reveals the evolutionary forces that shape the delicate and unique specificity characteristic of such interactions.
The presence of anti-CarP antibodies, anti-CCP2 and several ACPA specificities was investigated in order to describe populations of patients and pre-symptomatic individuals with overlapping and unique antibody specificities (Table 3).
