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Based on the information captured, the dependencies between specifications involved in the tracked process are identified and inserted in a dependency network, which is maintained throughout the design process.
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Low-level specifications involve changes in the level of protein activity or gene expression (e.g. over-expression of a given protein leads to a decrease of another protein).
We observed, however, that addition of the small molecule Wnt/β-catenin agonist CHIR-99021 between days 2 and 5 inhibited endothelial fate specification, indicating that other factors involved in the specification of endothelium tightly orchestrate the dosage of Wnt/β-catenin signaling (supplementary material Fig. S7).
The detailed specification of what is involved in such knowledge or understanding has not yet appeared in the literature, but some aspects of it are becoming well known.
WS-Agreement follows related contractual principles, allowing for the specification of the entities involved in the agreement, the work to be undertaken, and the conditions that relate to the performance of the contract.
Taken together, our microarray analysis results indicate that Lhx1 is involved in specification of the entire kidney field.
For example, D-cbl does not influence Torso [36], a RTK involved in specification of the termini in the Drosophila embryo [54].
Indeed, it is well documented to be involved in specification of mesodermal lineages [ 32].
As mesencephalic morphology was altered following fgf22 knockdown, we investigated whether fgf22 was involved in specification of the midbrain.
Recently, gene expression data sets have become available for the genes involved in specification of floral organ identity.
Thus, it is suggested that fgf22 is involved in specification of the tectum by controlling pax7a expression.
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CEO of Professional Science Editing for Scientists @ prosciediting.com