From literature, the DEVS formalism (Discrete EVent system Specifications) appears to be general enough to represent such dynamical systems (Zeigler et al., 2000).
Sony's specifications appeared to render the Dreamcast obsolete months before its U.S. launch, although reports later emerged that the PlayStation 2 was not as powerful as expected and distinctly difficult to program games for.
The results for this specification appear in column (2) of Table 5.
While a key role of Nodal in mesendoderm formation has been demonstrated in amniotes, amphibians and teleosts (Conlon et al., 1994; Erter et al., 1998; Feldman et al., 1998; Schier, 2009; Schier and Shen, 2000; Steiner et al., 2006), the mechanisms controlling the earliest phase of endoderm specification appear to vary extensively across vertebrates.
Notably, the ability to recruit Dsh to junctions, as seen during planar polarity specification, appears to require some specific residues in the Fz intracellular loops and C-terminal tail that have no major requirement in canonical signaling (magenta in Figures 2 and 6).
However, for a chain with two states, the current specification appears to be better since it involves a smaller number of parameters and offers a nice way to test for time dependence by testing the hypothesis λ=0.
Our preferred specification appears in columns 3 and 4 of Table 3: it is estimated for all states and includes state-specific time trends as well as dummies for CLM at different points in time surrounding the date of the repeal in the transition states.
; BT49B A BT49B specification appeared early in the 1980 season; it was conceived around a new transverse gearbox designed by American gearbox specialist Pete Weismann.
In all organisms, the main driver of centromere specification appears to be the assembly of specialised chromatin containing the histone H3 variant generally known as CENP-A and called as CID (Drosophila), Cse4 (S. cerevisiae) and Cnp1 (Schizosaccharomyces pombe).
