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Three studies did not meet the mentioned minimal scientific requirements (i.e., acceptable specification of exposure, blinding and test conditions, [ 44- 46]) and therefore were not included.
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It is important to note that the levels of noise exposures associated with these health effects range widely; as a result, the prevention of different health effects involves specification of different exposure limits and metrics.
The lack of prior literature on the appropriate specification of BPA exposure during pregnancy makes it difficult to determine if a single measurement or summary measurement of BPA concentration more accurately quantifies exposure.
Details of the sampling and measurement protocols can be found in Gauderman et al. (2005) and of the specification of the exposure prediction variables in Molitor et al. (2006).
More speculatively, generating instruments from within the data and performing split-sample or jackknife IV analysis, including bi-directional analysis, could allow resolution of causal direction within networks of phenotypes, without advance specification of which exposure or outcome is being examined (67).
Using separate U1, U2, and U3 uncertainty components allows for specification of correlations in exposure measurement errors across years and across individuals with shared exposure sources, in contrast to standard epidemiological models that assume independence of the measurement errors (Armstrong 1998; Rosner 2010).
All other estimated marginal probabilities are practically unaffected by this cardinal specification of the media exposure variable.
The magnitude of the health risk depends on arsenic specification, duration and frequency of exposure, and demographic factors (Anawar et al. 2002; Khan and Yang 2013).
The studies identified used a wide range of different procedural specifications such as time of exposure to agent.
Our analysis of HYSPLIT predictions against the satellite and monitoring data suggests that mis-specification of the magnitude of exposure as more likely source of error then mis-classification of day to day exposure status.
We investigated four realistic exposure mis-specification scenarios for this simulation study and found that performance of one calibration method may systemically outperform another depending on the type of exposure mis-specification.
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