The four Hox clusters A-D and Cdx1 were major Sp1 targets in Flk1+ cells (supplementary material Table S4), but not in progenitor cells (Fig. 4C, supplementary material Fig. S5F), indicating that Sp1 activity is directly required for correct activity of early regulators of hematopoietic specification at this specific developmental stage (Fig. 6C).
This template creates a chromatin signature that may be sufficient to maintain accessibility of promoters to basal transcription machinery, obviating the need for the induction of specific transcription factors to drive germ cell specification at each generation.
The segregation of these two derivatives should thus specifically rely on another signal that triggers myoblast specification at that particular developmental time.
Our gene expression analysis demonstrates that vasa, tudor, and boule are specifically expressed in PGCs beginning at the putative time of their specification at the embryonic posterior just prior to gastrulation.
Nakamura et al. (2006) reported that injected Wnt5α MO suppresses notochord formation, interfering with the early processes of notochord cell-fate specification at the cleavage stage by suppressing gene expression of a notochord-specific key transcription factor, Bra (brachyury), at the 64-cell stage.
Like many people, I bought a digital camera mainly on its specification: at the time, 1.3mp was considered good value for £599.
The current tally doesn't make for easy reading; just 16 of 156 GCSE and A-level specifications due to be taught next September have been signed off, while 14 of 21 subjects have no approved specification at all.
MySpace and Google demonstrated an interesting mashup of the MySpace Data Availability API, oAuth and the iGoogle gadget specification at the oAuth Summit a couple of weeks ago.
Elasticities: brackets indicate the range obtained in function of the specification at use or the confidence interval when available.
It is not possible to have random effects and the Heckman specification at the same time (in the software used: Stata).
