Sentence examples for specification and determination from inspiring English sources

These, along with eumetazoan-specific genes, later became essential components of the specification and determination of eumetazoan germ layers.

Although states of specification and determination both represent differential gene activity, the properties of embryonic cells are not necessarily the same as those of fully differentiated cells.

Within the embryo, specification and determination of mesoderm and endoderm in the primitive streak are regulated by BMPs, Nodal and Wnts (reviewed in [37]) and accompanied by an epithelial to mesenchymal transition.

Several transcription factors and signaling pathways have been shown to be important for RPE maintenance and differentiation, but an understanding of the initial fate specification and determination of this ocular cell type is lacking.

The anterior endoderm and cardiac mesoderm develop in close proximity to each other, both at early stages of lineage specification and determination, as well as later during organogenesis (reviewed [ 59]).

Fourth, it has identified cell-type specific transcriptional regulators with potential roles in mammary epithelial cell lineage specification and fate determination and has shown how these factors are likely to operate in a complex network.

Recently, it has been shown that Wnt signaling is also required for lung endoderm specification and progenitor fate determination [15].

Extensively investigated, the function of sox9 is known to be critical for many aspects of cell differentiation such as heart valve development, neural crest differentiation, chondrocyte specification and male sex determination in mammals [ 106- 109].

Analysis of trichome differentiation has revealed a complex gene network that directs and controls the cell determination, specification and differentiation process [ 48, 57, 58].

This second expansion particularly concerned the group A bHLH families, which contain tissue-specific transcription factors that control the determination, the specification and the differentiation of many cell types in bilaterians.

In most recent years, genome-wide technologies utilizing massively parallel DNA sequencing have begun to provide unbiased insights into the regulatory hierarchies of specification, determination and differentiation of ocular cells and neurogenesis in general.