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While CPAF exerts its cytoprotective effect by specifically stimulating the targeted degradation of the BH3 proapoptotic proteins, SidF neutralize Bcl-2 proteins with proapoptotic activities [43], [44].
Compounds specifically stimulating the Smad2/3 route should be developed.
On the soil surface, casts are rather heterogeneously distributed showing associations with certain plant species and thereby specifically stimulating their growth (Zaller and Arnone 1999).
The medicinal qualities attributed to the hotbed practice were physical recovery, protection against puerperal fever, alleviating symptoms of postpartum anaemia (dizziness and headaches specifically), stimulating expulsion of the lochia, ceasing postpartum bleeding, perineal healing and as lactagogue.
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In contrast, the BMDMs from these two mouse strains showed similar responses to poly (I C) (a TLR3 ligand) stimulation, indicating that PS-F2 specifically stimulates macrophages via TLR4.
91 The advent of recombinant allergen synthesis allowed the production of allergen isoforms that are not only hypoallergenic, i.e, with reduced IgE binding, 92, 93 but that specifically stimulate the production of protective antibodies (eg, specific IgG, IgA and IgM) and regulatory T-cells.
Among the p53-binding proteins that are described to influence the cellular outcome are the apoptosis-stimulating proteins of p53 (ASPP) proteins that interact with p53 and specifically stimulate p53-induced apoptosis but not cell cycle arrest and iASPP that inhibits p53-mediated apoptosis [7].
This occurs because they develop the ability to synthesize growth factors that specifically stimulate the formation of vessels.
Much of the immunoglobulin therefore must represent the product of all the B cells that are, so to speak, "ticking over" even if not specifically stimulated.
This report demonstrates that MLTF specifically stimulates transcription of the rat gamma-fibrinogen gene through a high-affinity binding site.
Only a small selection of films (especially those containing elastin fibres) specifically stimulated the proliferation of keratinocytes, but not fibroblasts.
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