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One interesting working hypothesis, supported by some preliminary data (not shown), would be that the apparent difference of specificity could more specifically result from differential control mechanisms of the substrate dependent initiation of oxygen activation cycle between CYP1A1s and CYP1A2s rather than from detailed features of substrate binding in the active site.
Thus, we consider that hyperferritinemia and this characteristic profile of cytokines specifically result from pathophysiology of RP-ILD with PM/DM, although the precise mechanism of hyperferritinemia in RP-ILD with PM/DM has remained unclear.
Importantly, the wtipMO or wtipMOex2 morphants phenotype could be rescued by the co-injection of wtip mRNA, demonstrating that the phenotypes specifically result from wtip knockdown (Fig. 2C; data not shown).
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Specifically, results from this work elucidate arctic temperature influence on detrimental failure mechanisms: large facesheet-core debonding, extensive composite facesheet delamination, significant core shearing and crushing, and severe facesheet fiber fracture.
We aimed to develop a framework for designing monitoring networks to detect trends in aquatic and semi-aquatic bryophyte communities, prioritizing high-conservation interest communities in different contexts of human pressure (specifically, resulting from the intersection of two criteria: (i) protection status and (ii) presence of a potential impact area).
Such injuries, specifically resulting from yoga, have been the subject of a kerfuffle recently, prompted by an excerpt of the book, The Science of Yoga: The Risks and Rewards, published in the New York Times Magazine, and written by science writer William J. Broad.
Moreover, the same angiogenic defects could also be induced by k-ras-MO2 (Figure 4B iii), demonstrating that the angiogenic defects are specifically resulted from K-ras knockdown.
Specifically, results from two Phase III trials 12, 13 suggest that laquinimod exerts a significant impact within the CNS.
The advantage of MGMT methylation testing is that if detected a methylation signal specifically results from the neoplastic glial cells.
To address next whether NO- and AMPK-mediated loss of SERCA2 expression specifically resulted from alterations in protein stability, INS-1 cells were treated with CHX combined with or without SNAP or AICAR.
Specifically, results from our association tests of all common mtDNA variants and the risk of CRC show that there is no single common coding-region mtDNA variant or haplogroup that strongly influences risk of developing CRC.
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CEO of Professional Science Editing for Scientists @ prosciediting.com