Exact(2)
This research reports small molecule anti-infectives which are specifically potent against several strains and isolates of TB.
Since biodegradation depends on environmental factors, including nutrients levels, availability of substrates, predation, population density, contaminant concentration, pre-exposure, and bioavailability [7], active microbial communities must often be either sustained with either metabolic substrates or specifically potent external communities.
Similar(58)
Our data demonstrate the potential risk associated with clinical application of broadly acting covalent epigenetic modifiers, and highlight the value of combination therapies that include agents specifically targeting potent pro-metastatic genes.
More specifically, the potent anti-angiogenic matrix glycoprotein thrombospondin-1 (THBS1), was significantly upregulated 14-fold in HCT116 cells at 24 h (Table 1).
More specifically, [11C]clorgyline, a potent and irreversible inhibitor of MAO-A, showed a mean 28%% reduction in MAO-A activity (ranging from 22 to 38%%) across all cortical and subcortical regions imaged [105].
For cocaine use disorders (CUD), specifically, the most potent intervention currently available for initiating abstinence is behavior therapy using contingency management (CM) procedures, with early cessation being a robust predictor of future abstinence.
Histatin-5 specifically has exhibited potent activity against C. albicans.
Despite the extensive available information on the association of C. albicans Saps and host protein degradation, in depth investigating into the ability of the Saps to degrade small salivary antimicrobial peptides specifically those with potent anti-candidal properties such as histatins, has not been fully investigated.
Specifically, target compounds displayed potent effects against various toxicities such as H2O2 and 6-hydroxydopamine (6-OHDA) in PC12 cells.
Telithromycin, the first of the ketolide antimicrobials, has been specifically designed to provide potent activity against common and atypical/intracellular or cell-associated respiratory pathogens, including those that are resistant to β-lactams and/or macrolide lincosamide streptograminB (MLSB) antimicrobials.
Some of these compounds (4h k, 4n, and 5e) have exhibited potent cytotoxicity specifically against human leukemia HL-60 cell lines with IC50 values in the range of 0.08 0.70 μM.
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