This domain-independent effect was specifically modulated by performance improvement.
List of DEGs specifically modulated in 3 h-treated root samples of Eurosis or Loto.
Activity of the hypothalamus – the major brain area controlling peripheral metabolism – is specifically modulated by insulin.
Because major differences in the stress response between the 2 cultivars were found in 3 h-treated roots, all of the DEGs specifically modulated in 3 h-treated root samples of Eurosis or Loto (3455 and 1410 genes in Eurosis and Loto, respectively; Table 3, Additional file 8: Table S8) were analysed using MapMan to identify differences in metabolic and regulatory pathways.
Multiclass analysis identified 2,777 probes for which expression was specifically modulated by C. burnetti infection.
The other three clusters, representing the majority of probes modulated by C. burnetii infection (86% of the total), are sex-dependent: 1,459 probes (53%) were specifically modulated in males whereas 892 (32%) were specifically modulated in females.
Two genes specifically modulated by C. burnetii, EGR-1 and NDRG1, likely play a major role in pregnancy.
Among them, 47 genes were specifically modulated by wt DRIL1 and not by any of the SUMO mutants.
Second, the full transcriptional response of murine macrophages to T. whipplei showed that T. whipplei specifically modulated the expression of 231 probes in IL-16−/− macrophages.
To determine whether neuronal GTs were involved, we measured EPSC weighted decay-time constant (τw), a parameter specifically modulated by EAAC1 in the striatum [22].
In this study, we made use of the QMb-ts myoblast model, which faithfully reproduces myogenesis in vitro, in order to identify novel miRNAs that are specifically modulated in both differentiation and maturation of skeletal muscle cells.
