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T cells specifically modified to express the GD2-specific chimeric receptor 14. G2a-28 ζ efficiently interacted with Ewing sarcoma cells, resulting in antigen-specific secretion of cytokines.
It is in fact a nanofiber whose surface chemistry can be site- specifically modified [1].
The properties of optical minigastrin probes can be specifically modified by the introduction of spacer sequences.
A high-grade medical polyurethane (PUR) was specifically modified to mimic the vascular vessel lumen.
Dynamic programming technique with specifically modified Longest Common Subsequence (LCS) algorithm is used.
Mice with specifically modified p53 tumor suppressor genes provide an interesting demonstration of this approach.
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In the last 10 years, methods to produce site-specifically modified histones have burgeoned.
This method generated site-specifically modified ADCs with a DAR of 2.0 in high purity.
However, when PTMs are distributed to different histones, the use of site-specifically modified nucleosomes to investigate the binding mechanism becomes imperative.
Fortunately, chemical biology has provided chromatin biochemists with a rich toolbox geared toward the assembly of site-specifically modified "designer" chromatin.
Full-length antibodies can be efficiently and site-specifically modified at the C-termini of their heavy chains by intein-fusion technologies.
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