Specifically, early work on breast epithelial cancer cell lines derived from a single spontaneous tumor arising in a Balb/C mouse demonstrated that the 'winner' phenotype of two related cell lines is independent of their intrinsic proliferative capacity when cultured alone (Miller et al. 1988).
Specifically, early escapees have larger fitness effects on the wild population if they affect density dependence before natural selection (i.e., hard selection, solid lines in Fig. 2E,F) than if they affect natural selection before density dependence (i.e., soft selection, solid lines in Fig. 2G,H).
Specifically, early maturing girls would show great reactivity to social stress compared to on-time maturing girls.
24 A retrospective analysis, focused specifically on early recurrence events occurring in BIG 1 98 (at 2 years), found a 30% reduction in early DM events with letrozole (87 vs 125 events, 2.3% vs 3.3%).
Gene expression patterns indicative of mutational status in ovarian cancers are discernible, but they are not highly predictive in out of sample validation with the exception of a signature developed specifically on early stage cancers.
Comparative phylogenetic dating of this duplication event suggests that it occurred early on, specifically in teleosts.
Specifically, QIDS did this early on by creating several formal partnerships provincial, local and national for the experiment.
These studies have evaluated recruit morality from competition with macroalgae and from predation by grazing organisms, but few studies have focused specifically on early-life survival from predation by corallivorous piscine species and even fewer studies have evaluated the influence of microstructure on juvenile coral survival from corallivory.
The two parted amicably, and Kleiner Perkins even served as an investor for Cowboy Ventures' first fund, which they raised in the Spring of 2012 to focus specifically on early-stage startups.
There had been a succession of books, two early on with a specifically serious purpose: The Pact (1978), written with Alistair Michie, on the Callaghan-Steel arrangement after Labour lost its majority, and Michael Foot: A Portrait (1981), with David Leigh.
