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In fact, the application of SELDI-ToF techadque had so far been limited to cell lysates for which the huge quantity of proteins represents a consistent obstacle to the clear identification of specific protein clusters specifically associated to PTCH1+/− fibroblasts and/or NBCCS patients with aggressive/mild clinical behavior.
As a result, each anesthesia type was in the end, not only descriptive, but also, specifically associated to a specific time of execution and a different use of human resources.
Recent data emerging from large integration site datasets predict the association of HIV integration sites with histone post-translational modifications specifically associated to transcribed chromatin rather than to enhancers, promoters and other regulatory regions [43].
The present study was designed to investigate whether the presence of periodic breathing is specifically associated to low post-conceptional ages, preterm birth, or common clinical disorders related to preterm birth.
The observation that expression of SYWT is more cytotoxic than expression of SYR621C in yeast disagrees with the initial reports that the R621C mutation would be specifically associated to PD [24].
To identify genetic polymorphisms specifically associated to CM, we used the strategy of comparing genotype frequencies between 130 patients with the CM syndrome and 158 patients with severe forms of malaria severe malaria in absence of CM (SnC).
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Circular dichroism spectroscopy, analytical ultracentrifugation, and thermal unfolding studies indicate that the A and B peptides specifically associate to form an A2B2 heterotetramer.
By analyzing Table 1, it is possible to verify that most of the 100 informative genes had already been described in the literature as genes related to cancer (76 genes) and 45 genes had specifically been associated to prostate tumor.
Importantly, unlike many other biomarkers that are correlated with patient outcome following tamoxifen treatment [ 2], CUEDC2 appears to be specifically associated with response to therapy, rather than with an inherently poor-outcome phenotype [ 9].
Importantly, unlike other investigators, Beelen and colleagues [ 2] were able to examine whether these mutations were specifically associated with response to tamoxifen but did not observe a statistically significant interaction between tamoxifen treatment and PI3KA mutation.
Moreover, it was suggested to be specifically associated with Hsp90α and to stimulate its ATPase activity [36].
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