Sentence examples for specific trail from inspiring English sources

TRAIL is a protein which causes apoptosis and death of cancer cells, without harming normal cells, by binding to specific TRAIL receptors and leading to activation of the extrinsic apoptosis pathway (Wiley et al, 1995).

Indications of non-compensatory behavior, and greater error variance among less experienced trail users were found in the partial profile experiment with more specific trail attributes, but not in the experiment with multidimensional attributes.

Thus, claims of general cancer type specific TRAIL receptor preference should be taken with a pinch of salt.

At 3 days after injection of effector cells, cryosections were prepared and stained with a specific TRAIL antibody.

An area where specific TRAIL variants and/or agonistic antibodies can be used with good predictability is in combination treatments, in which up-regulation of either TRAIL-R1 or TRAIL-R2 can be targeted by the respective variant.

Second this paper examines farmers' willingness to participate in a hypothetical walking scheme whereby the general public will be allowed access to specific trails.

Most specimens (28 of 36, 78%) had specific TRAIL-R1 staining on at least 20% of tumour cells.

Different wilderness areas and parks will have a variety of options available to backcountry hikers, so consult park maps of the area to find the specific trails, or find some online by checking out the National Parks website.

In this speculative case, the use of TRAIL death receptor-specific TRAIL mutants could serve as an option to reduce potential side effects related to activation of the TRAIL death receptor type not relevant for apoptosis induction in the targeted tumor type.

In keeping with a small molecule pharmacological approach, we describe here a novel screening strategy optimized for the detection of caspase-8 pathway-specific TRAIL sensitizers, and demonstrate its usefulness by a proof-of-concept screen.

To test this hypothesis we make the additional prediction that gender-specific trail following would be in the norm in two other littorinid species, L. obtusata and L. fabalis, that share the restricted mating season and low density with L. littorea, although their yearly egg production is similar to L. saxatilis [13].