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It is possible that their functional specificity is derived, at least in part, through specific temporal and spatial expression patterns.
Specifically, silk proteins such as fibroins and sericins are primarily produced in the posterior silk gland (PSG) and middle silk gland (MSG), respectively, and the genes that encode these factors exhibit rhythmic "on" and "off" transcriptional regulation during development, resulting in distinct and specific temporal and spatial expression7.
However, the experimental validation for both techniques, with differentiating sensitivity to the various neuronal activities at specific temporal and spatial resolutions, is still in progress and requires carefully designed magnetic field sensor technology.
While continuing down the path to discovery of new target genes, serious efforts are also focused on fine-tuning the expression of the known candidate genes for stress tolerance in specific temporal and spatial patterns to avoid negative effects in plant growth and development.
As a result, over-saturation of dissolved CO2 in rivers may be misestimated if the estimation is made based on a specific temporal and spatial scale.
Here we show that in the Inpp4awbl mutant, Purkinje cells are lost in a specific temporal and spatial pattern.
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Here we consider several mechanisms that have been suggested for how the Bithorax regulatory domains are able to bypass intervening boundary elements and direct the appropriate parasegment-specific temporal and spatial expression of their target gene.
This study examines site-specific temporal and spatial patterns of agricultural land use dynamics from 2001 to 2012 in a nine-county region of East-Central Iowa using the United States Department of Agriculture National Agricultural Statistics Service Cropland Data Layer.
Patient-patient similarity networks can represent complex disease patient populations; High-dimensional datasets can exploit the topology of re-defined clinical phenotypes; Additional genetic and experimental layers can be usefully added to identify specific biomarkers; Temporal and spatial aspects can be accounted for.
We feel that selecting an expression cutoff of ln TPM) = 0 is too strict for this analysis as many imprinted genes expressed below that level, that we carefully validated, have features of known and novel-validated imprinted genes expressed above that level, e.g., located in imprinted clusters, isoform-specific imprinting, temporal and spatial regulation, and associated with apoptosis.
One such mechanism is DNA methylation that has the capacity to establish and maintain diverse patterns of gene expression from the same genome under specific temporal, spatial and environmental conditions [ 3].
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