However, we believe that a more likely explanation could be the development of new antibodies that are more specific and technical differences in the histochemistry.
While there are many similarities, the changes in both size and functionality are also reflected in specific and instructive technical differences.
Let us leave, at least for now, the pleasures of side-by-side comparison to budding cineastes, who will learn a lot from studying the decisive difference that specific technical choices — having to do with editing, shot selection and sound design — can make with respect to the mood and meaning of a single story.
The lack of similarity could represent species-specific immune responses or simply technical differences – for example, Roxstrom-Lindquist [ 41] orally infected young male flies with bacteria, fungi and microsporidia, and measured whole-body gene expression changes in only two replicates using Affymetrix microarrays.
Due to biophysical and technical differences such as particle size, specific gravity, injected particle load, microembolization, and catheter placement, 99mTc MAA can never exactly replicate the post-radioembolization biodistribution of 90Y resin microspheres [12, 17].
So it is clear that specific effects are found despite the biological and technical differences between immortalized lymphoblastoid cells, grown in tissue culture, and assayed with Illumina microarrays and white blood cells directly isolated from blood and analyzed using Affymetrix Focus Genechips®.
However, our analysis suggests that the substantial difference between these may only in part be attributed to technical differences in sample ascertainment or analysis specifics.
Such features, and indeed any specific aspect of the pattern, could be reflective of real differences or be due to technical differences in the liberation, capture and sequencing of the nucleosomal DNA fragments.
Other than the technical differences between the experiments, we hypothesize that the proportion of the splicing patterns may be specific to different phenotypic conditions.
This may be due to technical differences such as concentration of interferons, microarray platform and gene annotation, but may also reflect cell-specific (professional immune vs non-immune) responses to IFN stimulation [54].
The system does have some specific technical requirements.
