However, the effectiveness of microbial degradation of highly chlorinated PCBs and specific substituted PCBs is limited [22].
Although a surgeon may prefer one specific substitute for reconstruction, modern knee surgery requires individual concepts and a variability of treatment options.
We find that the withdrawal of Vioxx had both positive and negative effects for specific substitute drugs in its own class (COX-2s), and that it led to an overall increase in the usage of both its most direct competitor class (NSAIDs) and in a class of older similar therapy (Analgesics).
In this work, a bioink composed by silk fibroin (SF) hydrogel combined with elastin was used to bioprint patient-specific substitutes mimicking IVD ultrastructure, in particular the outer region of the IVD (i.e. annulus fibrosus, AF).
One approach is to modify the intrinsic specificity of TRAIL for its target Death-receptor 5 specific by substituting amino-acids located in the receptor binding interface of TRAIL [ 8].
Tissue engineering aims to produce patient-specific biological substitutes in an attempt to circumvent the limitations of existing clinical treatments for damaged tissue or organs.
The limitations of natural tendon grafts motivate the tissue engineering (TE) approaches, which aim to build patient-specific biological substitutes that can repair the damaged or diseased tissues.
Tissue engineering (TE) aims at producing patient-specific biological substitutes in an attempt to repair, replace and regenerate damaged tissues or organs in order to improve the current state of clinical treatments.
To be specific, by substituting the transformed point density (41) and the transformed inertia profile (43) into the distortion integral given by (25), the corresponding upper and lower bounds of the average system distortion of a MISO CSI-quantizer with transformed codebook has the following forms: (44).
In our specific case, substituted dNTPs with lower leaving group p Ka's have atoms at the β γ-X-phosphate bridging position that are expected to show greater electron-withdrawing propensity.
Consecutively, a pump-controlled infusion of the rheologically relevant specific volume substitute was maintained (3.9 ml/kg per hour) beside a basic crystalloid infusion of 5.1 to 5.4 ml/kg per hour, which was suitable for keeping the animals' mean arterial blood pressure above 50 mm Hg.
