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But there were other more specific similarities: For instance, the equivalent of pogroms in America where whites would burn down black sections of a town, and gruesome experiments reminiscent of the ones conducted in WWII concentration camps.
Both programs allow for more than one sequence per species in an ortholog cluster, only when the intra-specific similarity for the sequences in the cluster is higher than the sequence similarity between species.
These weights are computed by a specific similarity metric for a given data source.
What are the specific similarities mentioned in the article between the current Avian flu (bird flu) and the 1918 pandemic?
There are specific similarities and characteristics that define this new trend.
Among the fungi, for example, the genomes of N. crassa and S. cerevisiae show no lineage specific similarities.
After extensive parameterization to find the most sensitive and specific similarity and coverage thresholds for fragment assembly using our algorithm (Additional files 1 and 2), a substantial proportion of ORF fragments could be so linked, ranging from 9.3% for S. clavuligerus ATCC27064 #2 up to 46.2% for S. roseosporus NRRL11379 (Table 2).
Hence, it was possible to determine which similarity threshold leads to higher F1 (optimal δ best) for a given search using a specific similarity function.
The profile is then optimized by adjusting the cutoff value for position-specific similarity assessment and used for a genome scan to search for unknown members of the regulon.
Beyond intra-specific correspondences, striking inter-specific similarities in terms of soma position and neurite projection patterns are assessable for most of the detected SL-ir neuron types.
Both drugs and targets are associated with domain-specific similarity measures; there are five measures for drug drug pairs and three measures for target target pairs, as described in Table 5. Dataset 4 is used to evaluate the quality of AnnSim with respect to a gold standard drug drug similarity measure.
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