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In the present study, our aim was to examine a specific set of genomic sequences and gene neighborhoods, targeted for study because they contain genes of likely relevance to horticultural and fruit quality traits, with emphasis on metabolic pathways, flowering-related genes, and disease resistance-related genes.
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Substantial progress in treatment requires identification of a specific set of actionable genomic abnormalities that drive or facilitate tumorigenesis, resistance to a given treatment and recurrence.
It is noteworthy that the clade 2 + 99-738 DP-B5 setcific set of genes includes genomic island XII identified by Cohen et al. [ 20] as being present in most clade 2 strains and missing from most clade 1 strains (genes VV2_1090 to VV2_1111 on the CMCP6 genome).
Either way, our results identify the presence of both histone H2A and H2B tail monoubiquitinations at genes that are targeted selectively for mutagenesis, identifying this specific set of chromatin modifications with genomic loci that are deaminated by AID and mutated by responding DNA repair pathways.
Our findings suggest that a specific set of periodic DNA motifs encoded in genomic DNA, which provide signals for chromatin organization, influence human chromosome function.
The advantage of this approach is that it is not limited to a specific set of genes, or the relatively small genomic regions around genes' transcriptional start sites.
For the confirmation of cellulase gene the gene fragment was amplified by PCR from genomic DNA using gene specific set of primers: celF (5′-ATGAAACGGTCAATCTC-3′) and celR (5′-CTAATTTGGTTCTGTTCCC-3′) [32].
For a specific tumor type, genomic aberrations often occur in a specific set of chromosomal hotspots.
Three azo-reductase genes were amplified from genomic DNA of P. aeruginosa (isolate B1) by PCR using specific sets of primers.
This allows GREAT to generate hypotheses about the regulatory functions of the set of genomic regions.
Then a set of genomic regions was randomly sampled.
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CEO of Professional Science Editing for Scientists @ prosciediting.com