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These findings confirm our previous findings of cancer-related, non-locus specific replication timing alterations of loci (that normally replicate synchronously) in blood lymphocytes of patients with a solid tumor (see Introduction).
An alternative is to specify a node specific replication probability, where nodes decide ad-hoc if a file is replicated or not.
Here we examined how specific replication conditions affecting replisome architecture and repriming impact on DDT.
However, there is no correlation between recombination and the specific replication fork pausing sites found at the tRNA SUP53 gene.
If, however, we take into account that genomes also encode for enzymes that perform replication and error correction, then individual genomes not only have a specific replication rate (fitness), but also a specific mutation rate.
To develop specific replication inhibitor at the molecular level, mono- and di-hammerhead ribozymes (Rz) were designed and synthesized against the conserved 3′ end sequences of HEV, which cleave at nucleotide positions 7125 and 7112/7125, respectively.
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Specific replication-related proteins show a preference to bind curved DNA sequences [ 12].
We also detect a wide range of variation in the abundance of specific replication-dependent isoforms of histone H2A.
The yeast Shu complex, consisting of Shu1/ Shu2/ Psy3/ Csm2, facilitates efficient HR repair of specific replication-induced lesions (Shor et al. 2005).
According to our results, each of the cancer patients had an allele-specific replication mode for loci that normally replicate in the classical biallelic-mode.
Source nodes keep an ordered list of neighbouring nodes and replicate each message to the top (the application-specific replication factor, which can also be thought of as a priority level).
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