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The present study defines and characterizes the economic burden of migraine in a patient population attending an Italian III level headache center by providing specific quantification of the cost associated to the episodic and chronic forms of disease.
Specific quantification of the cortical phenotype of Cx43 deficiency has been documented previously by our group [ 9, 21] and others [ 24, 34] using high-resolution microcomputed tomography.
The established qPCR method enables the ultrasensitive and highly specific quantification of the residual synthetic ssDNA test soiling on test objects.
For specific quantification of the human orthologue, we employed the Ab sandwich [hSA3/211-B] [hSA3/211-B]ntiforathen of total SNCA (i.e. mouse and human combined), we employed the sandwich pair [hSA3/Syn1-B], where 'B' stands for biotinylation).
For the accurate and specific quantification of the cell surface glycosylation profile, they further proposed a modified cell surface-capturing strategy, where the glycosylated-peptides were submitted to LC-MS/MS analysis directly for identification of glycosylated-proteins, and the nonglycosylated-peptides were isotopically labeled for quantification of glycosylated-proteins.
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D2O incubation of Q1-VSD in LPPG micelles for 2 h followed by acquisition of a H N TROSY spectrum provided site-specific quantification of the degree of replacement of backbone amide protons with deuterium.
In the variant-specific approach, the other internal monitoring peptide, TSATVGPK, allowed for the specific quantification of H2A.X histone, regardless of its phosphorylation status.
The formation of O2 was therefore measured with the fluorescent dye singlet oxygen sensor green (SOSG) allowing the specific quantification of O2 [ 26].
We recently reported a novel fluorescence (FL) reaction with 4-trifluoromethylbenzamidoxime (4-TFMBAO) reagent for the specific quantification of orotic acid22.
Immunoassays have been developed for the specific quantification of biomolecules in clinical diagnostics.
This increase was observed with both EGFR protein measurement and with the specific quantification of EGFR receptors (Table 2).
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