Sentence examples for specific predisposition from inspiring English sources

If BRCA-linked disease requires inactivation of check-point(s) followed by BRCA gene loss, then the tissue specificity of BRCA-linked disease might arise from a specific predisposition of the breast and ovarian epithelium to lose the function of such checkpoints.

Sex specific predisposition to cancer may reflect the underlying effects of the methylation patterns of key cancer genes.

BRCA1 epimutations mainly occurred in early-onset BC (5.5%) and familial OC patients (8%) and, therefore, may be associated with specific predisposition for these types of cancer.

We concluded that the correlations uncovered between miRNA loss and rhythmic gene expression parameters were not likely to have arisen by chance, for example as a result of a specific predisposition of the data structure or distribution that could have occurred in our particular time series and the downstream analyses.

Be sure to keep in mind that this information is not meant to replace conventional diagnoses but should be seen in the context of providing information that might identify specific predispositions.

Thus there appear to be specific predispositions determining the path stuttering will take.

Many epidemiological studies so far have reported higher rates of non-fatal suicidal behaviour in females which could indicate a gender-specific predisposition for the experience of suicidal thoughts and suicide attempts during this life-period [ 6, 15, 16].

Clark and Watson introduced the tripartite model in which general distress is viewed as a personality trait – "negative affectivity" – that is underlying depressive and anxiety disorders as a non-specific predisposition [ 20].

We suggest that this discrepancy can be attributed to racial differences, indicating the need to perform genetic association studies in different ethnic populations to identify race-specific predisposition genes.

While these unexpected results remain unexplained, the replication within species and the contrast to other species suggest that they may reflect a species-specific predisposition, for example a preference for a smaller over a larger non-food object that needs to be handled or moved.

Second, the tissue specificity of TSG hypermethylation in sporadic cancer overlaps with the tissue-specific predispositions caused by inherited mutations in these same genes.