Limitation to IgG3 in our three cases confirms the specific predilection for IgG3 to precipitate and self-aggregate in the glomeruli given its properties of high molecular weight, positive charge and complement activation capacity [ 7].
SB100X has a number of advantages over virally mediated gene delivery: it integrates transgenes exclusively into TA dinucleotides with specific predilection for dinucleotides that have distinct structural features, integrates transgenes with high efficiency, results in stable integration, integrates large inserts, and does not primarily integrate into transcriptional sequences [ 42– 42].
The reasons for the specific predilection of HCV for infecting exocrine gland tissue are unknown.
Both possibilities may be active in this case, resulting in an apparent context-specific predilection for ISCU1/2 to be subject to net down-regulation.
Furthermore, in the commonly used Han:SPRD rat model, where the mutation is in the Pkdr1 gene [ 11], there appears to be a male gender-specific predilection for p21 attenuation, which is consistent with observed gender dimorphism of disease severity in clinical and experimental studies [ 12, 13].
However, a sex specific predilection to risk factors for venous thromboembolism, apart from use of hormonal therapy and pregnancy, seems unlikely.
Bill Milbrodt from Howell, N.J., wrote, "if you are in the information-delivery business and want a message to have a specific twist brewed for a specific predilection, this is one hell of a story to learn from".
Postmortem studies indicate that iron content and lifespan differences therein are regionally specific, with a predilection for the basal ganglia.
Bias may arise because specific V regions' CDRs have a predilection for specific Ags or binding orientations on MHC molecules [12], [27], [28].
Similar to the previously reported context-specific target gene predilection for miR-21 in PH (Parikh et al, 2012), the apparent favoring of ISCU1/2 as a target of miR-210 in the hypoxic pulmonary endothelium is not an uncommon scenario in miRNA biology where, with increased specific miRNA expression, only a subset of its validated gene targets may display a net down-regulation.
Even their questionable predilections for graven images and an inclusive afterlife are ultimately authorized by kabbalah.
