This is due to the need for specific placement of the enzyme on the viral ends on long substrates [17].
The needle track can be used as a marker for specific placement of the injection system (see below).
The specific placement of the adsorbed polymer chains on the solid surface depends, among others, on the molecular weight of the polymer, its kind (anionic, cationic, and nonionic), concentration, and type of surface groups of the metal oxide, solution pH, and temperature.
Site-specific placement of the claMP Tag within EGF allows for correct folding and disulfide-bond formation, confirming that precise placement of the claMP Tag can be used to generate a bioconjugate that retains native structural elements and, importantly, its functionality.
The specific placement of epigen within the EGF receptor ligand branch depends on the method of generating the tree, while the other newly identified ligand, NGC, segregates with IMP2 and the mucins near the split between the EGF receptor and ErbB3/ErbB4 ligands, interesting considering the characterization of NGC as only binding to ErbB3 [ 5].
In view of the latter possibility the specific placement of Alu-sequences in the upstream flanks of GA-sequences may even offer a certain quantitative control of background protein synthesis: If each GA-sequence has its own upstream Alu-sequence, the genome navigation mechanism(s) may produce proportionally as many copies of Alu-transcripts as they opened loops for transcription.
The specific placement of each element in the sequence is essential to the sequence's function (consider, for example, the "syntactic chain" in rodent grooming behaviour, Aldridge and Berridge 1998; Berridge et al. 1987).
Some of these cases appear to result from the specific placement of long branches in the "anti-Felsenstein zone", where biased estimation can increase the efficiency of finding the correct topology [ 52, 54].
Although a specific placement of ELF3 in the plant circadian network has not yet been determined, the ELF3 protein seems to interact with components of both the morning- and evening phased circuits of the current three-loop model.
Both trees were highly concordant for the species-level clades but differed on the specific placement of some clades (Additional files 8 and 9).
The denser sampling however allowed testing specific placement of species, showing, for example, that the unusual Australian Plebidonax deltoides is not a member of Donacidae and instead nests within Psammobiidae, suggesting that major revision of Tellinoidea may be required.
