Sentence examples for specific pathological states from inspiring English sources

Altered dopamine signaling is associated with specific pathological states such as Parkinson disease and schizophrenia, as well as drug addiction.

Since a disease will normally affect and alter one or several biological processes, we could depict a theoretical multidimensional "gene space" divided in regions that include genes associated to specific pathological states.

The construction of gene networks related to specific disease subtypes that include parameters such as gene-to-gene association, gene disease specificity and gene discriminant power can be very useful to draw gene-disease maps and to unravel the molecular features that characterize specific pathological states.

Obesity-associated organ-specific pathological states can be ensued from the dysregulation of the functions of the adipose tissues, liver and muscle.

Obesity-associated organ-specific pathological states can be ensued from the dysregulation of circulating levels of adipokines and metabolites and ectopic fat storage within organs that normally do not accumulate fat, e.g. liver and muscle.

Behaviour therapies are aimed at correcting specific pathological emotional states or behaviour patterns through appropriate countermeasures.

The progression of Tau pathology was followed using anti-Tau antibodies specific for different pathological states of the Tau protein: a hyperphosphorylated state (AT8 [ 35]), a conformational change (MC1 [ 36, 37]) and an aggregated form (AT100 [ 38]) already validated in this model [ 22].

However, the role of specific subtypes in normal and pathological states remains poorly understood due to the lack of selective probes.

To ascertain if PD prevents muscle wasting by downregulating the UPS, protein levels of atrogin-1/MAFbx, a muscle-specific ubiquitin ligase overexpressed in pathological states associated with muscle atrophy [4], [7], were evaluated.

However, it is not clear for any of the brain's neuromodulatory systems how neurons releasing these neurotransmitters are controlled to promote specific behavioral outcomes in normal or pathological states, and how experience modulates their release.

Therefore, different trimester-specific reference ranges were defined to distinguish physiological alterations from pathological states [ 13– 15].