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One specific mutation in the flies' genes can lead to a "sleep initiation deficit".
"We treat people with the specific mutation who may benefit," David Schenkein, the C.E.O. of Agios, told me.
There is no conceivable way for haemoglobin to cause a specific mutation in the virus that would enhance its virulence.
The current focus has changed to trying to identify the patient's mutation and then using a cocktail of different drugs tailored for that specific mutation.
Once you know which mutation has been inherited in a particular family, then other family members can be screened for that specific mutation by blood tests," explains Wishart.
The donor was carrying a specific mutation that prevents HIV from attacking white blood cells.
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Upper: the transgenic plant without the target mutation; lower: the biallelic mutant with the site-specific mutation.
However, our results cannot rule out site-specific mutation proneness.
Strand-specific mutation bias has been supposed to be the main force driving and maintaining the codon usage bias [2].
The multispecies coalescent allows for gene-specific mutation rates.
The position-specific mutation scores at residues i and j and their neighboring residues are used.
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