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QMC employs the monomolecular tetrahelical architecture of DNA and has two key components: (i) shape complementarity between QMC partners, which is introduced by specific modifications of the quadruplexes, and (ii) Mg2+ ions.
In particular, we show that both overtone and combination modes have essential contribution to the 2D band, bringing about specific modifications of the band shape.
Most studies on surface-initiated controlled polymerizations for the synthesis of polymeric covalent organic-inorganic hybrid materials focus on chemical methods requiring specific modifications of the inorganic substrate.
Recent advances in understanding these complex systems have also informed the targeted manipulation of biosynthetic pathways to produce specific modifications of the final natural product.
Here we are reporting the discovery of novel and selective anaplastic lymphoma kinase inhibitors from specific modifications of the 2,4-diaminopyridine core present in TAE684 and LDK378.
Their formation involves specific modifications of the steroid nucleus and formation of a carboxylic acid group that is linked to the amino acids taurine or glycine to give the forms in which the bile acids are secreted into the bile.
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The analysis is based on a specific modification of the transfer matrix formalism previously introduced for one-dimensional TAP-reactor models.
A STEM gel is comprised of a network with latent initiating sites allowing for the post-synthesis, spatially specific modification of the matrix.
Active targeting for cells has explored specific modification of the liposome surface by functionalizing it with specific targeting ligands in order to increase accumulation and intracellular uptake into target cells.
A specific modification of the two variable expansions is used, where the non-smooth (triangle wave) temporal argument is viewed as a fast time while the energy decay is described in a slow time scale.
The specific modification of the interfacial properties of finely dispersed TiO2-powders by adsorbing surface-active substances (polyacrylic acid) causes a change of dispersity and flow behaviour of TiO2-suspensions.
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