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This study has examined the effect of (i) incorporating the EDIIIs of four DENV serotypes into a single chimeric antigen, and (ii) immobilizing the antigen through specific interaction on the sensitivity and specificity of anti-DENV antibody detection.
The first results, partly presented in the present work, are very much encouraging showing the specific interaction on Multi Walled and Single Walled carbon nanotubes.
It is difficult to imagine a system in which a species shows specific interaction on a short time scale, but reverts to non-specific interaction as it approaches an equilibrium partitioning.
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This recognition is based on the specific interaction of target molecule with the detection part of the nanoprobe.
Immunosensors, based on a specific interaction of antibodies with their corresponding antigens, provide a sensitive and selective tool for the detection of many kinds of proteins.
Using a biochemical screening assay based on the specific interaction of this C-terminal peptide and UL42, several potent small molecule inhibitors were identified [43].
Rac1 and Rac2 activity was measured by the affinity-precipitation assay based on the specific interaction of the activated Rho-GTPases with their downstream effectors [19].
Indeed, sorting of ER membrane residents depends on the specific interaction of motifs mainly located in their cytoplasmic tails.
The FAP system is uniquely suited to studying trafficking; fluorescent signals are generated based on the specific interaction of the dye-binding peptide and fluorogen dyes.
This strategy relies on the specific interaction of the EVH1 domain of Ena/VASP proteins with a proline-rich motif (D/EFPPPPXD/ED/E) [ 5].
Thus, the relief of oligomerization and aggregation by cosolubilization of NDSBs does not rely on the specific interaction of the NDSBs with the compounds or proteins.
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