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Moreover, intracrine/nuclear heregulin might also bypass the antiproliferative effects of HER-directed TKIs without need for activation of specific HER RTK members or HER network-driven activation of downstream signalling cascades.
The simple, perfect drawings in the museum that conveyed the burdens shouldered by a woman bathing or a young girl dancing were as universal as the particular pattern of my wife's breast cancer was specific — her mass, her possibly involved lymph nodes.
Most accuse Cyrus of appropriating twerking from black culture, but Azalea claims Cyrus lifted her signature dance move from somewhere more specific: her.
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Thus, it is extremely unlikely that recall bias issues would apply only to those cases in a specific HER-2/ neu status subgroup.
Thus, in the future, the specific HER-2 mutation identified could be used to direct choices regarding the optimal HER targeted therapy.
Allogeneicity and recombinant IL-12 were previously needed as adjuvants in HER-2 cell vaccines to break tolerance to HER-2 in transgenic HER-2 mice, eliciting a specific anti-HER-2 humoral response (Nanni et al, 2001).
That the interaction between MD.45-HER/ ζ CTL with the tumour cell target was specific for HER-2/neu was best shown using the HER-2/neu transfectants.
In order to help the participant to reach her BMI-specific recommendation, her rate of weight gain was monitored until the end of pregnancy by using a BMI-specific weight gain chart [ 38].
Eventually it turned against her, although we don't learn anything specific about her reaching rock bottom.
The HER-2/neu oncoprotein may serve as an excellent target for developing anticancer agents specific for HER-2/neu overexpressing cancer cells.
Vaccinated mice produced specific anti-HER-2 human IgG.
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