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We and others have described that miRNAs are abnormally expressed in CLL and have specific expression patterns in CLL subtypes (9 13).
In B. rapa, these genes exhibited either predominant or specific expression patterns in leaves, such as BrZEP1, which was highly expressed in flowers and leaves.
These results indicate that some large subunit genes may show specific expression patterns in plants.
By crossing these Gal4 lines with UAS-mCD8 GFP; UAS-mCD8 GFPlies, we confirmed their specifliesxpression patterns in MB lobes (Fig. S1).
In vitro experiments using explants from the embryonic lateral telencephalic neuroectoderm reveal that exogenous BMP proteins (BMP4 and BMP2) induce expression of Msx1 and inhibit Bf1 expression, a finding consistent with their specific expression patterns in vivo.
Furthermore, some genes show specific expression patterns in certain tissues at certain stages, suggesting the involvement of epigenetic mechanisms in the development of these systems.
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Interestingly, some miRNAs showed very specific expression pattern in one tissue but not other tissues that are examined here.
Most transcripts showed specific expression pattern in root and shoot at early, middle or late stage of −P and ++P stress.
Its highly specific expression pattern in TG, DRG and parasympathetic neurons and the presumed role in abating neuronal excitability under inflammatory conditions make it an excellent target for development of new migraine therapeutics [59, 60].
Given their specific expression pattern in the amphioxus, their conservations between amphioxus and human, and the crucial functions of their human homologies in the immune system, it's reasonable to propose that these miRNAs may participate in shaping the "pre immune system" in the amphioxus, and play conserved roles during immune system evolution.
For instance, whether PsPIP2 1 had a tissue specific expression pattern in root endodermis and/or leaf bundle sheath that are proven to be critical in the pathway of plant water transport, as well as the responsiveness of PsPIP2 1 to abiotic stresses (e.g., drought stress), all merit future investigations.
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