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Further, type I and type II divergence analyses were carried out for the GGT clades showing positive selection for the identification of specific divergent sites which might be contributing to the functional divergence.
The OdH2A.Z variant exhibits the specific divergent characteristics with respect to H2A.1 described for universal H2A.Zs, including a highly positive N-terminal tail, a divergent L2, and divergent self-dimerization and docking domains.
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The tissue-specific difference in protein stability can potentially be due to differences in total chaperone levels indicating a tissue-specific divergent induction of the HSF1-mediated heat shock response.
We identified 26 human-specific (divergent) sites (data not shown).
This suggested that Irs belong to two subgroups: conserved antennal Irs and species-specific divergent Irs.
These findings suggest that GmaPHO1 genes may exert certain roles in soybean development with lineage-specific divergent patterns.
IRs were further classified into two sub-families: conserved "antennal IRs" involved in olfaction and species-specific "divergent IRs" that might be associated with gustation [ 37, 38].
The location affected by the mutations is part of the cardiac-specific divergent region 3 (domainmain) of RyR2, which is believed to be involved in regulation of the Ca2+ release channel (6).
The first was branch-specific divergent pairs with the pair being rearranged in the other two species, including 11.7% of rice divergent pairs but only 4.4% of sorghum pairs (Table 3, two species).
The study is centered on the identification of conserved IntFams (cIntFams) across all nematodes that have the potential for broad-spectrum pan-nematoda control, while species or clade-specific divergent IntFams (ncIntfams) represent novel functions.
We annotated nine new candidate HarmIR genes, five of which (IR60a, 64a, 68a, 75p.1 and 93a) were well clustered into conserved antennal IRs and the remaining ones (IR2, 7d.1, 7d.2 and 7d.3) were classified into species-specific divergent IRs.
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