This could induce specific linkage disequilibrium in the area of rearrangement.
However, the causal gene and variant at a specific linkage disequilibrium block is often unclear.
However, a heterozygote deficiently coupled with high genetic diversity and population specific linkage disequilibrium may indicate recent admixture.
Parent-specific transmission disequilibrium tests were performed using sib_tdt from the ASPEX package (http://aspex.sourceforge.net/).net/
It is possible that population-specific linkage disequilibrium with another functional variant could be operating.
The determination of gene-specific linkage disequilibrium (LD) patterns in desi and kabuli based on single nucleotide polymorphism-microsatellite marker haplotypes revealed extended LD decay, enhanced LD resolution and trait association potential of genes.
These regions can be detected because of their lower genetic variability and specific regional linkage disequilibrium (LD) patterns.
These deviations are most likely due to local inbreeding effects as shown by the high inbreeding coefficients (FIS > 0, Table 1) and the lack of loci specific patterns of disequilibrium.
In this method, there was no specific modelling of linkage disequilibrium evolution: linkage disequilibrium was complete at time 0 on the mutated haplotype and remained complete during the following generations.
This approach utilizes population-level disequilibrium among specific inbred lines of mice to identify loci associated with disease traits or other complex phenotypes of interest.
