Sentence examples for specific destruction from inspiring English sources

These co-activators provide APC substrate specificity by facilitating the recognition of specific destruction motifs (e.g. degrons) such as the D-box (RxxLxxxxN) or KEN box (Lys Glu Asn) (King et al., 1996; Min and Lindon, 2012; Pfleger and Kirschner, 2000).

Time and temperature requirements to achieve specific destruction of the pathogens were calculated from the thermal destruction parameters, and the efficacy of the RFDH process was validated by heating NDM using RFDH to achieve the target temperatures and holding the product in a convection oven for the required period.

The Doa10p complex ubiquitinates membrane proteins with malformed cytosolic domains and soluble cytosolic proteins bearing specific destruction signals (8 11).

6 Olieman et al. 7 demonstrated by angiography findings of specific destruction of tumor vessels after perfusion with TNF-α, leaving the normal vasculature unchanged.

Understanding the specific destruction of the network in specific diseases and at specific stages is the key starting point for subsequent design of rescue or remedial strategies.

We wondered how they might impact type-1 diabetes (T1D), hallmarked by specific destruction of the insulin-producing β cells of the pancreatic islets (Bluestone et al., 2010).

Mitosis-specific destruction of GATA1 selectively delayed post-mitotic reactivation of GATA1-bookmarked genes [ 16].

These signatures precisely reproduce those observed in humans during immune-mediated tissue-specific destruction (TSD) that causes tumor or allograft rejection, autoimmunity or clearance of pathogens.

Tumour-activated TIL induced TH1 phenotype change in MSCs that is qualitatively similar to the previously described immunologic constant of rejection signature observed during immune-mediated, tissue-specific destruction.

The systemic administration of both nanostructured drugs in a colorectal cancer xenograft mouse model promotes efficient and specific local destruction of target tumor tissues and a significant reduction of the tumor volume.

Interestingly, concentric lesions in subjects who do not suffer from Baló's sclerosis are described in either ischemia, such as stroke [12] and cyanide poisoning (in cats and rabbits, [13]), or in cases where a specific oligodendrocyte destruction occurs, such as attacks by JC [14] and HHV6 [15] viruses.