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These corresponded to the loss of specific copies of the DAZ, CDY1 and BPY2 gene families.
Based on alignment scores and the presence of unique exons, we were able to unequivocally assign two clones to specific copies of YTHDC2 (Additional file 2: Figure S2B).
Upright letters are used when referring to families and subfamilies, and italics are used for specific copies (i.e., the HELPO1.1 subfamily vs the HELPO1.1 element).
At least 20 clones of each PCR product were sequenced, and all the primers used could amplify the specific copies of OpdCYC and OpdcyclinD3 genes.
If there were male-function or meiosis specific copies in sexual rotifers [ 19, 20], bdelloids might be expected to have lost those copies or for them to have evolved new functions.
Differential expression of a specific copy of the duplicated cell cycle regulatory gene CDC20 and specific copies of histone H2A suggest that such duplications may underlie the phenotypic plasticity required for reproductive mode switch in monogononts.
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We work with a specific copy pipeline equipped with different copy modes which are all possible combinations of mono/color, text/mix/picture/photo, and periodic/stochastic.
The genome sequences of the six individuals were used to identify individual specific copy number variations as compared to NCBI Build 37. Table 5 shows the distribution of observed CNVs in MZ twins representing the two families.
Many possible candidates have been proposed, including specific copy number variations, NOTCH4, and histone protein loci.
Regions of allelic imbalance were determined using the allele specific copy number (AsCN) function of Partek.
K27M-H3.3 DIPGshoweded specific copy number changes, including all gains/amplifications of PDGFRA and MYC/PVT1 loci.
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