Sentence examples for specific conjugation from inspiring English sources

Small protein ligands can provide superior physiological distribution compared with antibodies, and improved stability, production, and specific conjugation.

Streptavidin-labeled horseradish peroxidase (Streptavidin-HRP) was subsequently immobilized on the electrode surface via the specific conjugation of biotin and streptavidin.

Efforts to use the cytoskeletal filaments for applications often require chemical or genetic engineering of the filaments such as specific conjugation with fluorophores, antibodies, oligonucleotides or various macromolecular complexes e.g. nanoparticles.

Site specific conjugation, which has been achieved through a variety of methods and can result in very tight DARs and increased homogeneity (Junutula et al., 2008; Panowski et al., 2014; Perez et al., 2014; Beerli et al., 2015; Ihospice et al., 2015; Siegmund et al., 2016; Thompson et al., 2016; Tsuchikama and An, 2016; Beck et al., 2017), appears to be a significant advancement.

The fluorophores in use today are either chemical entities requiring site specific conjugation or genetically encoded molecules [ 4, 5].

The use of DNA, RNA, and protein as building blocks in nanotechnology has an advantage over the chemical materials in their eligibility for site-directed modification and specific conjugation with defined stoichiometry.

The development of novel site-specific conjugation technologies enables the systematic study of architectural features within the antibody conjugated drug linker that may affect overall therapeutic indices.

It is becoming increasingly clear that site-specific conjugation offers significant advantages over conventional conjugation chemistries used to make antibody drug conjugates (ADCs).

We have previously reported a novel site-specific conjugation platform comprising linker payloads designed to selectively react with site-specifically engineered aldehyde tags on an antibody backbone.

Thus, (chemo enzymatic approaches generally allow for site-specific conjugation leading to tightly controlled DARs.

The 122cys residue in the mutant fragment is available for site-specific conjugation.