The motivation of earlier work [ 18– 23] seems to be mainly exploratory – to find specific cases of nonlinear interactions, but not to "solve" genetic architectures involving hundreds or thousands of loci.
However, except for these very specific cases of host-parasite interactions, little is known about what kind of effect digested microbes, even naturally occurring essentially non-pathogenic microbes, have on insect immunological ecology.
A possible exception to this view corresponds to the specific case of genetic interaction networks [5].
Moreover, there are specific cases of long range RNA-RNA interactions in Dengue [ 49]; however, usually the interactions between the RNA, and the replication and translation machinery are expected to prevent 'long range' RNA folding (due to its unfolding by proteins and factors related to these steps), but still enable generating local mRNA structures.
To test the roles of disorder in the specific case of protein-protein interaction networks, we first collected a set of structurally characterized hub proteins [ 127].
In the specific case of a physical interaction between two proteins, and log-transformed data, the formula above corresponds to the law of mass action, as follows.
The GEIRA program aims at detecting gene-environment as well as gene gene interactions, and in this first report, we describe both the generic algorithms, and their application in a specific case of gene-environment interaction.
Although, in this study, we analyzed the specific case of a tumor interaction with an oncolytic virus, it is our hope that these techniques will prove useful in other systems that include interaction between tumor cells and anticancer agents.
Here, we present a surface proteomic approach to test this hypothesis in the specific case of biomaterial-epithelial cell interactions.
Although this is one specific case of all the proteins in interactions or non-interactions, we found this visual differentiation between the different protein types to be encouraging and opens up directions of future research relating 3D structure of proteins and dimers concentrations.
In the specific case of isotactic polypropylene (iPP), any interaction of the carbon nanotubes with the polymeric host has minimal effect on the frequency of the MWCNTs G band (∼1584 cm−1); the same holds for the influence of residual stresses acting on the MWCNTs.
