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However, numerous induced genes were found to be associated with more specific annotations of potential functional relevance (table 1 and supplementary data 3).
This model of nucleolar localisation thus increases the coverage while providing accurate and specific annotations of the nucleolar proteome.
The two more specific annotations of PRIAM are not included in the AcypiCyc database as they did not pass the cut-off point applied in the generation of the database using CycADS [ 56].
The systems approach presented here for predicting host-virus protein interactions will benefit from ongoing research on the more specific annotations of short linear motifs and domains involved in protein-protein interactions.
Measures of conservation can be used to identify regions of the genome where variation is expected to be more deleterious, even in the absence of specific annotations of functional elements.
For the first three approaches, A' is the set of specific annotations associated with the reference gene used for the transfer; for the OPI approach, A' is the set of specific annotations (plus the specific annotations of the upper levels) that have been predicted for g with a FDR below the cutoff.
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In fact, more than two-third of the non-tRNA ligase genes preceded by a T-box lacked such a specific annotation of molecular function.
Publications describing (molecular-) cytogenetic analyses of tumor samples and established cell lines are mined for case specific annotation of the experimental results.
Cell-type specific annotation of research resources in immunology can rely on ontologies to enhance data integration, sharing and collaboration among researchers.
The cell-type specific annotation of resources within the Directory provides a significant improvement in the way researcher can access, share and relate information.
Still missing, however, are transcriptome-specific annotations of the CC founder strains that could further enhance the utility of this resource.
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