Sentence examples for specific and severe from inspiring English sources

However, some patients develop specific and severe toxicities, since these molecular targets are also expressed in normal cells.

These data demonstrate that the consequence of the homozygous p. (Gln48*) PET100 variant is a specific and severe loss of COX subunits and fully assembled complex IV.

However, the potential for serious injury or death remains, as freshwater cyanobacteria under bloom conditions are capable of producing potent toxins that cause specific and severe dysfunction to hepatic or central nervous systems.

Because the symptoms described in the vignettes are quite specific and severe, they might not pick up foregone care in relation to diseases that are more difficult to recognise or more chronic in nature.

25 Second, because the symptoms described in the vignettes are quite specific and severe, they might not pick up foregone care in relation to diseases that are more difficult to recognise or more chronic in nature.

If we consider IPD, the most specific and severe manifestation of the pneumococcal infection, its incidence is low (approximately 10-20 cases per 100,000 all-age inhabitants)[ 1] and prospective randomized controlled trials (RCTs) generally failed to demonstrate a significant protective effect of PPV against this outcome.

Exclusion criteria included specific pathology and severe causes of back/neck pain such as malignant disease, vertebral fractures and severe or progressive neurological symptoms.

However, removal difficulties still exist and induce specific and potentially severe complications.

Almost fifty years later, citrus growers are contending with a malady that is both more specific and more severe — and the counsel is far less comforting.

No one suggests the answers will be easy, but other societies from Northern Ireland to Israel have learned to adapt, albeit to threats more specific and less severe.

They must take specific, and increasingly severe, actions from curbing lending to closing a bank as a bank's capital ratios deteriorate.