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That we are a nation of immigrants is obvious, but the events leading up to the birth of the nuclear age give specific and profound meaning to this platitude.
It has become increasingly clear that the so called "non-coding RNA" exerts specific and profound functional control on regulation of protein production and indeed controls the expression of all genes.
What we mean by that is something very specific and profound: that because of drug use, a person's brain is no longer able to produce something needed for our functioning and that healthy people take for granted, free will.
I could go into a whole discourse about what's happening and why, about the dynamics of the American electorate, but I'm writing you to share one specific and profound reason the polls are so close: Young people are not showing support for Hillary Clinton.
Here, we demonstrate a specific and profound IFN-γ-induced, STAT1-dependent up-regulation of miR-29a and -29b in melanoma cells and importantly, also increased expression in primary melanoma patient samples (but not in metastatic tumors) whereas the second cluster pri-29b-2~c was consistently undetectable.
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Parents and teachers were asked to estimate each child's mental age, and teachers reported whether a child had a written statement of special educational needs related to cognitive and intellectual needs (including specific, moderate, severe and profound intellectual difficulties, but not distinguishing between them).
These alterations in dopamine and sigma receptor binding in offspring following prenatal cocaine and rearing by maternal dams are sex specific and could have profound effects on the development of behavior.
Your question raises two distinct questions, one general and profound, the other specific and practical.
All probability is conditional; judgment and profound knowledge of the specific topic are critical to accept that the findings of association studies are plausible in the light of what is known.
Bioinformatics' original focus was very specific, profound, and important, indeed, most articles in this Journal fall within the original discipline.
Very elemental and profound.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com