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There is an apparent link between NBTs aggressiveness and specific genetic aberrations (i.e., MYCN amplification, chromosome deletions of 1p36, 11q23, 14q32 or 19q13.3; gain of 17q and near-diploid/tetraploid DNA content), indicating that specific genetic alterations are present in individual categories of NBTs and likely contribute to clinical outcome [ 2- 4].
They identified specific chromosomal alterations linked to different stages of tumor progression and liver metastases and found that the majority of chromosomal alterations were present in both primary carcinomas and liver metastases.
Statin treatment was initiated 6 hours after CLP, when profound hemodynamic alterations were present.
In all, the alterations were present in the germ-line.
All alterations were present in the germ-line.
BBB ultrastructure alterations were presented through transmission electron microscope.
hrHPV-specific alterations are printed in bold.
This alteration is present in low frequency in Caucasian populations (4-6).
This sequence alteration was present on both strands and is not a known SNP; unfortunately DNA from normal tissue from the same individual was not available, so it is not possible to establish whether this is a tumour-specific change.
The specifics are present.
In this location, bone alterations are often present.
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