Sentence examples for species selectivity from inspiring English sources
Alternatively, more novel perm-selective barriers are being explored for species selectivity [42].
These data suggest that BPA is a species-selective agonist of hPXR, but not mPXR and rPXR, similar to the species selectivity of RIF for hPXR compared with mPXR and rPXR.
Deng, X. et al. Fluorine modulates species selectivity in the triazolopyrimidine class of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors.
Additionally, species selectivity (human, rat, mouse) and receptor subtype selectivity (P2X4 vs P2X1, 2, 3, 7) were investigated for selected derivatives.
To understand the species selectivity in a series of α-methyl-α-phenoxy carboxylic acid PPARα/γ dual agonists (1 11), structure-based molecular modeling was carried out in the ligand binding pockets of both human and mouse PPARα.
Traditional approaches use modified commercial fishing gear (such as trawls and baited hooks) that have biases in species selectivity and may also be inappropriate for deployment in some habitat types.
The properties that are shared by human and parasite kinases that suggest that effective parasite kinase inhibitors can be discovered on the basis of prior knowledge also raise concern about potential cross-species selectivity.
These results improve our understanding of the mechanisms of ADA ligand recognition and species-selectivity, and facilitate the rational design of novel EHNA-based ADA inhibitors as anti-malarial drugs.
We hypothesise that species-selectivity is at least partly determined by differences in metabolism based on in vitro data generated in liver preparations from rats, mice and guinea pigs.
The flexibility characteristics of the tunnel will be used to answer questions such as: What is the origin of species-selectivity of antibiotics binding?
Gratifyingly, however, the long-chain inhibitors (AMTS17 AMTS20) showed unprecedented AChE species-selectivity, causing only 0 to 2% inhibition of the RBC AChE (Figure 5) but 99% inhibition of the greenbug enzyme.
