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Each biological species (elements) in the model is either "ON" (present) or "OFF" (absent).
The most important classes are species, describing reactive species, and reactions, which interconnect species elements.
For example, in BIOMD0000000087, SBML's species elements are used to represent temporal stages.
The species elements in Figure 1 are both annotated with MIRIAM-compliant terms.
Percentage similarities are presented based on exact matching of names/ids for Compartments, Reactions and Species elements in the models.
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A species element can be further specified with the aid of MIRIAM annotations (Novère et al., 2005).
For example attributes such as name (associated with most SBML elements), initialAmount and initialConcentration (associated with the Species element) are captured as properties with the same names.
For example, a metabolite species element annotated with a ChEBI term will return a ChebiTerm object, providing a method for accessing the chemical formula of the metabolite.
Saint suggests the SBO term 'macromolecule' (SBO 0000245), which is added as an sboTerm attribute of that species element, as the best SBO match to a protein.
For instance, in Akman2008 Circadian Clock Model2 SBML model, there is a species element which has id MF and name Frq mRNA.
In addition, the species information is also included in tp:name by using parentheses, e.g., (h) for Homo sapiens and (m) for Mus musculus, although there is the tp:species element for describing species.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com