Our analysis also indicates that the present-day distribution of sterol enzymes in the different eukaryotic organisms analyzed is the consequence of differential losses that probably accompanied specialization of the pathways along with eukaryotic diversification.
The relatively low number of GPCR mutants with defects in more than one of the analyzed stages suggests either specialization, participation in pathways not uncovered during our study, or gene redundancy in the predicted GPCRs.
Tco89 is only found in S. cerevisiae and could have resulted from a specialization of the pathway exclusive to Saccharomyces species (Table 1).
It is likely that the specialization of each pathway can play a key role in regulating the biosynthesis of specific end products during olive fruit development.
Finally, the specialization of the different pathways could occur as a result of specialization of paralogous enzymes.
There is a relative specialization of the signalling pathways of macrophage reprogramming in response to different components of the microenvironment.
We qualitatively analyzed the data to identify factors students consider when developing specialty preferences, to understand their views about primary and subspecialty care, and to construct models depicting the pathways to specialization.
Based on these properties, we predicted that there should be a collection of differentially expressed genes between HVC and Shelf and that the identification of these genes would provide important clues as to molecular and biochemical pathways representing specializations of HVC and possibly involved in different aspects of HVC function.
The diversity and specialization found in biological molecules, pathways, and cells is staggering, and should be exploited for therapeutic use.
The model consists of the autocorrelation mechanisms, the interaural cross-correlation mechanism between the two auditory pathways, and the specialization of the human cerebral hemispheres for temporal and spatial factors of the sound field.
Based on the model of auditory brain system which consists of the autocorrelation mechanism, the interaural cross-correlation mechanism between both the auditory pathways, and the specialization of human cerebral hemispheres (Y. Ando 1998 Architectural Acoustics, Blending Sound Sources, Sound Fields, and Listeners New York: AIP Press/Springer-Verlag), a new diagnostic system was developed.
