The LLCP scenario also predicts a special locus, the Widom line, in the T P phase diagram at which the water response functions are at their maximum values7.
Because of the special locus of this gene, it can be deduced that this gene may associate with many diseases, and this hypothesis was confirmed by many research results [ 2, 3].
Many special intersecting loci which were not chosen by hand occur inevitably, notably codimension-three loci which are not intersections of matter curves.
Long stretches of satellite repeats may reside in a special chromosomal locus as a hallmark, functional unit, or a driving force for genome revolution[ 47].
Although only one locus, AT4G16280, remains statistically significant after controlling for multiple tests, several of these loci deserve special attention, and all of them should be considered candidate genes that require further examination in the future.
Loci of special interest also include genes encoding cytotoxic T-lymphocyte-associated protein 4 (CTLA4), protein tyrosine phosphatase-22 (PTPN22), and IL2 receptor alpha (IL2A).
Specifically, we were interested in: i) estimating the number of MHC class IIB loci, with special emphasis on expressed loci, ii) comparing patterns of diversity among expressed and pseudogene sequences to infer the mechanisms driving their evolution and iii) evaluating the relationship of the collared flycatcher MHC class IIB sequences with the MHC II of other Passerine species.
But this is almost admitting that these loci are special, indirectly reinforcing a selectionist interpretation, whereby the effects of purifying and adaptive selection did interchangeably create opposite patterns of diversity.
That journey promises to be a challenging one, and even the first strides can be hard, as you leave behind a place that has been the locus of special friendships and personal growth.
