A study finds that transcript translation and complex assembly are partitioned, and OXPHOS complexes III, IV and V are built at spatially defined regions of the mitochondrial inner membrane.
The capability to engineer microenvironmental cues to direct a stem cell population toward multiple fates, simultaneously, in spatially defined regions is important for understanding the maintenance and repair of multi-tissue units.
Uniquely, EMAGE searches can be made using spatially defined regions, as well as standard text based querying.
With the ability to add cues to the matrix after initial formation, spatially defined regions of various cues of interest can be created toward directing the organization and function of cells in three dimensions.
Specifically, toward application in culture and directing hMSC fate, gels could be patterned with individual or multiple biochemical cues in spatially defined regions to drive cellular processes, including adhesion, migration, proliferation, or differentiation.
This study presents on-tissue proteolytic digestion using a microwave irradiation and peptide extraction method for in situ analysis of proteins from spatially defined regions of a tissue section.
Furthermore, by utilizing a synthetic peptide cross-linker with a pendant functional group, we are able to introduce additional chemical moieties into the material at later time points or in spatially defined regions.
It can be envisioned that safe delivery of a nonparalytic clostridial chimera into spatially defined regions measuring as little as one cubic millimeter might be effective in blocking seizure-generating areas for several months.
Such spatially defined brain regions where neurogenesis occurs display a permissive microenvironment for the maintenance and differentiation of neural stem cells and to their proliferation.
Each region is spatially defined, and features of its oceanographic setting that are known or likely to affect marine biodiversity are described.
Utilizing a capacitive charge build-up on the surface of silicon, the region of stimulation is spatially defined by the diameter of the photocurrent induced from a beam of light.
