The real beauty of the system is that, because the ultimate measurement occurs in situ (in intact cells in their native positions), it both preserves the spatial relationships of cells and allows for measurements of other features, such as gene expression.
Cholinergic amacrine cells have terminal processes that stratify in both the ON and OFF sublayers of the IPL [36], and the spatial relationship of cholinergic cell processes with the dendrites of some different types of RGCs has been well examined [37], [38].
The close spatial relationship of serotonergic varicosities to peripheral cells however indicates that serotonin also acts on this cell type.
And efforts are currently under way to create the first detailed 3D map of the spatial relationship of all the organelles in a eukaryotic cell.
To examine this model, we have analyzed the spatial relationship of dopaminergic and serotonergic nerve fibers to the various cell types.
Figure 3 The spatial relationship of the source model.
Spatial relationship of protein signals was determined by interactively scanning through the image stacks.
This model emphasizes the temporal and spatial relationship of expression for each gene.
Thereby, we unraveled the spatial relationship of newly deposited plaques to pre-existing plaques in detail.
As discussed, advances in in vivo imaging techniques to monitor trafficking of immune cells have recently been developed and will be crucial for dissecting the temporal and spatial relationships of donor and recipient T cells, B cells and APCs in these models (Panoskaltsis-Mortari et al., 2004).
Jensen, U. B., Lowell, S. & Watt, F. M. The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis.
