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Interestingly, the spatial impairments found in Williams syndrome have been likened to those with right hemisphere damage [60].
Here we attempt to investigate deficits of sustained attention and its interaction with spatial impairments in right-hemisphere neglect patients using a set of novel visual tasks.
Moreover, sustained attention deficits in neglect have not specifically been related to PPC lesions, and it remains unclear whether they interact with spatial impairments in this syndrome.
In our study, by mapping performance deficits to lesion location, we hoped to elucidate the neuroanatomical basis for deficits of sustained attention and its interaction with spatial impairments in our neglect population.
Spatial impairments in Parkinson's disease are independent of executive skills (Cronin-Golomb and Braun, 1997) and depend on the integrity of posterior parietal cortex and a fronto-parietal network (Cohen et al., 1996; Zacks, 2008).
Lesions of the lateral mammillary nucleus yield surprisingly modest and transient spatial impairments, at least when compared with complete mammillary body or mammillothalamic tract lesions (Vann & Aggleton, 2003, 2004; for review see Vann, 2010).
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Most commonly, the individual suffering from cognitive symptoms of HD is aware of his or her visual spatial impairment.
Reading difficulties may also be the result of visual spatial impairment; however, the inability to maintain attention may be a contributing factor as well.
The Post Office will be on the left side of the street with a flag pole in front". For an individual suffering from visual spatial impairment, directions using "left" and "right" or geographic markers are easier to follow because they do not require the individual to orient his or her body in a particular direction.
We sought to understand the neural substrate of the spatial impairment caused by DNRAbs.
Importantly, despite a pronounced spatial impairment, Rgs7 −/− mice performed normally in the visible platform version of water maze.
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