Sparse seed banks, however, may lead to future declines of already rare species.
The first, "stringent" phase reports reads with near-perfect matches to the reference genome by using long and sparse seed substrings (seed length of 0.5 times the average read length, constrained to a minimum of 9 and a maximum of 31; seed spacing equal to 1 plus 0.25 times the square root of the read length, rounded down) and a stringent alignment score threshold (0.9 times the read length).
Operationally, this is accomplished by randomly seeding sparse regressions that define candidate modules with genes.
The linear representation was intrinsically sparse, because seed voxels were highly correlated with spatially neighboring voxels due to the averaging effect of BOLD signals and spatial smoothing.
As a general example, in a pairwise comparison of genomes popular alignment tools rely on a specific order of elements for each genome sequence, and on a set of sparse shared seeds that should then be extended to obtain a global alignment.
Dose response studies were performed with sparse melanoma cell cultures seeded in duplicate or triplicate wells (∼5,000 cells/cm2) in regular medium without or with increasing concentrations of Aza (0.1 1 µM) for 2 days, with fresh drug-containing medium on the second day.
In the scaffolds that were seeded with control cells, cell growth was sparse, and as a result, the spaces between the atelocollagen matrix remained mostly empty.
The typical cultivated phenotype displays a bush-type growth habit with a stout primary stem and sparse branches, bearing large seeds with variable seed coat colours, while the wild phenotype is a procumbent or climbing vine with a slender, many branched stem bearing small, coarse black seeds.
To identify whether the piloting axon was guided inside or outside, we seeded low-density cultures on an array of binocular-shaped SiN x microtubes, so the neurons were sparse enough to avoid forming bundles.
