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Furthermore, distribution of AChR clusters remained sparse in diaphragms of meltrin β−/− newborns, and the average size of AChR clusters was smaller in meltrin β−/− than in wild-type muscles (Fig. 1L).
Similar(59)
MCP-1 mRNA was not detected in control diaphragms, but was greatly increased in the diaphragms of septic animals.
Hypercapnia largely abolished the increases in levels of inflammatory cytokines in the diaphragm of ventilated rats.
Furthermore, upregulation of MAFbx mRNA expression has been found in the diaphragm of patients with emphysema, which is consistent with a reduction of diaphragm myosin content [24].
Diaphragm from these mice had lesser degrees of myotonia than seen in the diaphragm of the present study.
We found increased expression of iNOS in the diaphragm of these animals.
The flexible diaphragms result in greater floor displacements compared with rigid diaphragms of equivalent buildings.
For a more accurate determination of MyHC content in diaphragm, MyHC concentration (that is amount of myosin per muscle volume) was measured in diaphragm single fibers.
The detection of an accumulation of CUG expanded RNA as foci in diaphragm muscle fiber nuclei is another indication of the abnormality of the DMSXL diaphragm.
*p < 0.05, **p < 0.01 Fig. 5 Expression of biological markers in diaphragm tissue.
In addition, use of mechanical ventilation can result in diaphragm inactivity and atrophy [ 27- 30].
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